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Literature summary for 2.1.1.353 extracted from
- Dissection of the late steps in aureothin biosynthesis (2006), ChemBioChem, 7, 37-39 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + demethylluteothin | Streptomyces thioluteus | - |
S-adenosyl-L-homocysteine + luteothin | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptomyces thioluteus | Q70KH3 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + demethylluteothin | - |
Streptomyces thioluteus | S-adenosyl-L-homocysteine + luteothin | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AurI | - |
Streptomyces thioluteus |
| gamma-pyrone methyltransferase | - |
Streptomyces thioluteus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | in aureothin biosynthesis, methyltransferase AurI transfers the SAM methyl onto the alpha-hydroxyl group of the pyrone ring of demethylluteothin i.e. nordeoxyaureothin, to yield luteothin, i.e. deoxyaureothin | Streptomyces thioluteus |
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Release 2023.1 (January 2023)
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